EXOC1 Antikörper (AA 701-800) (AbBy Fluor® 488)

Produktnummer ABIN6943332

Produktdetails anti-EXOC1 Antikörper (AbBy Fluor® 488)

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Bindungsspezifität: AA 701-800

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOC1 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu EXOC1

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Andere Bezeichnung: EXOC1 (EXOC1 Produkte)

Synonyme: CG3885 antikoerper, Dmel\\CG3885 antikoerper, Sec3 antikoerper, sec3l1 antikoerper, zgc:64145 antikoerper, wu:fb58e03 antikoerper, SEC3L1 antikoerper, MGC165876 antikoerper, DKFZp459K086 antikoerper, BM-102 antikoerper, SEC3 antikoerper, SEC3P antikoerper, 2810407P21Rik antikoerper, A730011E05Rik antikoerper, Sec3l1 antikoerper, Sec3p antikoerper, Secretory 3 antikoerper, exocyst complex component 1 antikoerper, Exocyst complex component 1 antikoerper, Sec3 antikoerper, LOC475149 antikoerper, exoc1 antikoerper, EXOC1 antikoerper, LOC582238 antikoerper, LOC100566235 antikoerper, Exoc1 antikoerper, sec-3 antikoerper

Hintergrund:

Synonyms: BM-012, exoc1, EXOC1_HUMAN, Exocyst complex component 1, Exocyst complex component Sec3, FLJ10893, SEC3, SEC3 like 1, SEC3L1, SEC3P.

Background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Exo70, also known as EXOC7 (exocyst complex component 7), EXOC1 or 2-5-3p, is a 735 amino acid peripheral membrane protein that is a component of the exocyst complex. Localized to the cytoplasm and the cell membrane, Exo70 plays an essential role in the docking of exocystic vesicles to target sites on the plasma membrane and, specifically, may be involved in insulin-induced protein docking within the cell. Four isoforms of Exo70 are expressed due to alternative splicing events.

Gen-ID: 55763

UniProt: Q9NV70

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis