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EXOSC5 Antikörper (AA 141-235) (AbBy Fluor® 647)

EXOSC5 Reaktivität: Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN6943380
  • Target Alle EXOSC5 Antikörper anzeigen
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Bindungsspezifität
    • 14
    • 9
    • 2
    • 1
    • 1
    • 1
    AA 141-235
    Reaktivität
    • 17
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 26
    • 5
    Kaninchen
    Klonalität
    • 28
    • 3
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EXOSC5 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 12
    • 12
    • 12
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human EXOSC5
    Isotyp
    IgG
    Top Product
    Discover our top product EXOSC5 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Andere Bezeichnung
    EXOSC5 (EXOSC5 Produkte)
    Synonyme
    si:ch211-194n6.2 antikoerper, zgc:153707 antikoerper, EXOSC5 antikoerper, RRP41B antikoerper, RRP46 antikoerper, Rrp46p antikoerper, hRrp46p antikoerper, p12B antikoerper, D7Wsu180e antikoerper, exosome component 5 antikoerper, exosc5 antikoerper, EXOSC5 antikoerper, Exosc5 antikoerper
    Hintergrund

    Synonyms: Chronic myelogenous leukemia tumor antigen 28, CML28, EXOS5_HUMAN, EXOSC 5, Exosc5, Exosome complex component rrp46, exosome complex exonuclease RRP46, Exosome component 5, exosome component Rrp46, hRrp46p, p12B, Ribosomal RNA processing protein 46, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of, Ribosomal RNA-processing protein 46, RRP41B, RRP46, Rrp46p.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.

    Gen-ID
    56915
    UniProt
    Q9NQT4
    Pathways
    SARS-CoV-2 Protein Interaktom
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