Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), ChIP DNA-Sequencing (ChIP-seq), Dot Blot (DB)
Kreuzreaktivität
Human
Aufreinigung
Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Immunogen
Polyclonal antibody raised in rabbit against the region of histone H2A containing the acetylated lysine 5 (H2AK5ac), using a KLH-conjugated synthetic peptide
Optional[synonyms]: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.