KDM4A Antikörper
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- Target Alle KDM4A Antikörper anzeigen
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM4A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
- Immunogen
- Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein
- Top Product
- Discover our top product KDM4A Primärantikörper
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anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 141-310) antibody
KDM4A Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 932-1057) antibodyKDM4A Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 6E10G4 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A Reaktivität: Human ELISA, IHC, ICC Wirt: Maus Monoclonal 5H1 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 585-815) antibodyKDM4A Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 127-364) antibodyKDM4A Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A Reaktivität: Human DB, ICC Wirt: Maus Monoclonal 3559D5a unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (pTyr547) antibodyKDM4A Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB26167 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 527-559), (N-Term) antibodyKDM4A Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB10787 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (Center) antibodyKDM4A Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IF() - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.6 μg/μL
- Buffer
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- Andere Bezeichnung
- JMJD2a (KDM4A Produkte)
- Hintergrund
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Synonyms: JHDM3A, KDM4A, JMJD2, Lysine-specific demethylase 4A
Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Isoform 2: Crucial for muscle differentiation, promotes transcriptional activation of the Myog gene by directing the removal of repressive chromatin marks at its promoter. Lacks the N-terminal demethylase domain.
- Gen-ID
- 9682
- UniProt
- O75164
- Pathways
- Warburg Effekt
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