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KCTD17 Antikörper (AA 1-100) (Biotin)

KCTD17 Reaktivität: Ratte, Maus ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN6943867
  • Target Alle KCTD17 Produkte
    KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
    Bindungsspezifität
    • 14
    • 7
    • 2
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 16
    • 16
    • 12
    • 2
    • 2
    • 1
    • 1
    Ratte, Maus
    Wirt
    • 24
    • 2
    Kaninchen
    Klonalität
    • 26
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCTD17 Antikörper ist konjugiert mit Biotin
    Applikation
    • 13
    • 13
    • 12
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Cow,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KCTD17
    Isotyp
    IgG
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
    Andere Bezeichnung
    KCTD17 (KCTD17 Produkte)
    Hintergrund

    Synonyms: BTB, BTB/POZ domain-containing protein KCTD17, FLJ12242, FLJ98761, KCD17_HUMAN, KCTD17, Potassium channel tetramerisation domain containing 17, POZ domain-containing protein KCTD17, RP5-1170K4.4.

    Background: Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).

    Gen-ID
    79734
    UniProt
    Q8N5Z5
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