KCTD17 Antikörper (AA 1-100) (AbBy Fluor® 350)
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- Target Alle KCTD17 Produkte
- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KCTD17 Antikörper ist konjugiert mit AbBy Fluor® 350
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Cow,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human KCTD17
- Isotyp
- IgG
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
- Andere Bezeichnung
- KCTD17 (KCTD17 Produkte)
- Synonyme
- N28155 antikoerper, AA414907 antikoerper, AW742389 antikoerper, 2900008M13Rik antikoerper, RGD1311154 antikoerper, potassium channel tetramerization domain containing 17 antikoerper, potassium channel tetramerisation domain containing 17 antikoerper, KCTD17 antikoerper, Kctd17 antikoerper
- Hintergrund
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Synonyms: BTB, BTB/POZ domain-containing protein KCTD17, FLJ12242, FLJ98761, KCD17_HUMAN, KCTD17, Potassium channel tetramerisation domain containing 17, POZ domain-containing protein KCTD17, RP5-1170K4.4.
Background: Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).
- Gen-ID
- 79734
- UniProt
- Q8N5Z5
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