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MDFI Antikörper (AA 101-200) (AbBy Fluor® 647)

MDFI Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN6944053
  • Target Alle MDFI Antikörper anzeigen
    MDFI (MyoD Family Inhibitor (MDFI))
    Bindungsspezifität
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    • 33
    • 10
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 30
    • 2
    • 2
    Kaninchen
    Klonalität
    • 33
    • 1
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MDFI Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 12
    • 12
    • 12
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Spezifität
    In Mice, there is possible cross-reactivity with Glycoprotein endo-alpha-1,2-mannosidase (67 % homology with immunogen sequence, 53 kDa)
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MDFI
    Isotyp
    IgG
    Top Product
    Discover our top product MDFI Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MDFI (MyoD Family Inhibitor (MDFI))
    Andere Bezeichnung
    MDFI (MDFI Produkte)
    Synonyme
    MDFI antikoerper, I-MF antikoerper, I-mfa antikoerper, I-mf antikoerper, RGD1560271 antikoerper, MyoD family inhibitor antikoerper, MDFI antikoerper, Mdfi antikoerper
    Hintergrund

    Synonyms: I MF, I mfa, Inhibitor of MyoD family a, Mdfi, MDFI_HUMAN, MyoD family inhibitor, Myogenic repressor I-mf, OTTHUMP00000016375, OTTHUMP00000016376, OTTHUMP00000196103, OTTHUMP00000196414, OTTHUMP00000196415.

    Background: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).

    Gen-ID
    4188
    UniProt
    Q99750
    Pathways
    Maintenance of Protein Location
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