METAP2 Antikörper

Produktnummer ABIN6944076

Produktdetails anti-METAP2 Antikörper

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser METAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within C-terminal human Methionine Aminopeptidase 2.

Klon: 2G3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu METAP2

Target: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Andere Bezeichnung: METAP2 (METAP2 Produkte)

Synonyme: metap2 antikoerper, MGC53792 antikoerper, METAP2 antikoerper, GB13458 antikoerper, DDBDRAFT_0190923 antikoerper, DDBDRAFT_0304991 antikoerper, DDB_0190923 antikoerper, DDB_0304991 antikoerper, 4930584B20Rik antikoerper, A930035J23Rik antikoerper, AI047573 antikoerper, AL024412 antikoerper, AU014659 antikoerper, Amp2 antikoerper, Mnpep antikoerper, p67 antikoerper, p67eIF2 antikoerper, MAP2 antikoerper, MNPEP antikoerper, wu:fb98h06 antikoerper, zgc:66250 antikoerper, methionyl aminopeptidase 2 L homeolog antikoerper, methionyl aminopeptidase 2 antikoerper, methionine aminopeptidase 2 antikoerper, methionine aminopeptidase antikoerper, methionyl aminopeptidase 2 S homeolog antikoerper, methionyl aminopeptidase 2b antikoerper, metap2.L antikoerper, METAP2 antikoerper, metap2 antikoerper, LOC551771 antikoerper, CAALFM_C604080WA antikoerper, Metap2 antikoerper, metap2.S antikoerper, metap2b antikoerper

Hintergrund:

Synonyms: Methionine aminopeptidase 2, Initiation factor 2-associated 67 kDa glycoprotein, Peptidase M, MetAP 2, p67, p67eIF2, METAP2, MNPEP, P67EIF2

Background: Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.

Gen-ID: 10988

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling