METAP2 Antikörper
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- Target Alle METAP2 Antikörper anzeigen
- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser METAP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within C-terminal human Methionine Aminopeptidase 2.
- Klon
- 2G3
- Isotyp
- IgG
- Top Product
- Discover our top product METAP2 Primärantikörper
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anti-Methionyl Aminopeptidase 2 (METAP2) (AA 2-212) antibody
METAP2 Reaktivität: Human WB, IHC, IHC (p), IF, FACS Wirt: Maus Monoclonal 1F6 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 313-449) antibodyMETAP2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-478) antibodyMETAP2 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 437-467), (C-Term) antibodyMETAP2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4959-4960 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 95-144) antibodyMETAP2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Fledermaus, Hamster, Affe, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Monoclonal 8F2 unconjugated Recombinant Antibody
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 10-40), (N-Term) antibodyMETAP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB5103 unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) antibodyMETAP2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (C-Term) antibodyMETAP2 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Methionyl Aminopeptidase 2 (METAP2) (AA 1-220) antibodyMETAP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
- Andere Bezeichnung
- METAP2 (METAP2 Produkte)
- Hintergrund
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Synonyms: Methionine aminopeptidase 2, Initiation factor 2-associated 67 kDa glycoprotein, Peptidase M, MetAP 2, p67, p67eIF2, METAP2, MNPEP, P67EIF2
Background: Methionine aminopeptidases (MetAP), also designated peptidase M proteins, are members of the M24 family of proteins. Both MetAP-1 and MetAP-2 release N-terminal amino acids, usually methionine, from nascent peptides and arylamines. Eukaryotes contain both MetAP-1 and MetAP-2, whereas prokaryotes possess only the MetAP-1 enzyme. MetAP-1 and MetAP-2 control cell proliferation in mammalian cells. MetAP-2 is highly conserved between human and Saccharomyces cerevisiae. Neurofibromin (NF1) regulates MetAp-2 and increased expression of MetAP-2 correlates with several forms of cancer. Inhibitors of MetAP-2 are potential targets in cancer therapeutics, particularly in NF1-associated tumor proliferation. Chemotherapeutic drugs such as ovalicin and fumagillin bind to the active site of and inhibit MetAp-2.
- Gen-ID
- 10988
- UniProt
- P50579
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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