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Nesprin3 Antikörper (AA 201-300) (Biotin)

C14orf49 Reaktivität: Human, Maus, Ratte WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN6944256
  • Target Alle Nesprin3 (C14orf49) Antikörper anzeigen
    Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 201-300
    Reaktivität
    • 46
    • 39
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 46
    • 1
    Kaninchen
    Klonalität
    • 46
    • 1
    Polyklonal
    Konjugat
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Nesprin3 Antikörper ist konjugiert mit Biotin
    Applikation
    • 40
    • 18
    • 13
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Nesprin 3
    Isotyp
    IgG
    Top Product
    Discover our top product C14orf49 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
    Andere Bezeichnung
    Nesprin 3 (C14orf49 Produkte)
    Synonyme
    C14orf49 antikoerper, NET53 antikoerper, Nesp3 antikoerper, 4831426I19Rik antikoerper, nesprin-3 antikoerper, spectrin repeat containing nuclear envelope family member 3 antikoerper, spectrin repeat containing, nuclear envelope family member 3 antikoerper, SYNE3 antikoerper, Syne3 antikoerper
    Hintergrund

    Synonyms: C14orf49, Chromosome 14 open reading frame 49, FLJ25605, MGC75267, Nesp3, Nesprin3, Nesprin-3, NET53, Nuclear Envelope Spectrin Repeat Protein 3, Spectrin Repeat Containing, Nuclear Envelope Family Member 3, SYNE3, SYNE3_HUMAN.

    Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells

    Gen-ID
    161176
    UniProt
    Q6ZMZ3
    Pathways
    Maintenance of Protein Location
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