NMDAR2A Antikörper (pSer1232)

Produktnummer ABIN6944293

Produktdetails anti-NMDAR2A Antikörper

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Bindungsspezifität: pSer1232

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMDAR2A Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This phosphorylated site is homologous to that of Ser1232 in Mouse and Rat.

Homologie: Human,Mouse,Rat,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NMDAR2A

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Andere Bezeichnung: NMDAR2A (GRIN2A Produkte)

Synonyme: NMDAR2A antikoerper, nr2a antikoerper, GRIN2A antikoerper, EPND antikoerper, GluN2A antikoerper, NR2A antikoerper, glutamate ionotropic receptor NMDA type subunit 2A antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antikoerper, glutamate receptor ionotropic, NMDA 2A antikoerper, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antikoerper, GRIN2A antikoerper, grin2a.L antikoerper, LOC100438553 antikoerper, Grin2a antikoerper

Hintergrund:

Synonyms: NMDAR2A (phospho S1232), p-NMDAR2A (phospho S1232), GRIN2B, Glutamate [NMDA] receptor subunit epsilon 1, Glutamate [NMDA] receptor subunit epsilon 2, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-2, GRIN2A, hNR2A, hNR3, N methyl D aspartate receptor subtype 2A, N methyl D aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2A, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDAR2A, NMDAR2B, NMDE2_HUMAN, NR2A, NR2B, NR3.

Background: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Gen-ID: 2903

UniProt: Q12879

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity