Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RAB7A Antikörper

RAB7A Reaktivität: Human, Maus, Ratte WB, IHC, IHC (p), FACS, IF (cc) Wirt: Kaninchen Monoclonal 8H10 unconjugated
Produktnummer ABIN6944733
  • Target Alle RAB7A Antikörper anzeigen
    RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
    Reaktivität
    • 51
    • 23
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 47
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 44
    • 8
    Monoklonal
    Konjugat
    • 24
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser RAB7A Antikörper ist unkonjugiert
    Applikation
    • 31
    • 20
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Human RAB7 aa 50-150
    Klon
    8H10
    Isotyp
    IgG
    Top Product
    Discover our top product RAB7A Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
    Andere Bezeichnung
    RAB7 (RAB7A Produkte)
    Synonyme
    RAB5 antikoerper, PRO2706 antikoerper, RAB7 antikoerper, Rab7 antikoerper, rab7 antikoerper, pro2706 antikoerper, RAB7A antikoerper, LOC100231734 antikoerper, ARABIDOPSIS RAB GTPASE HOMOLOG G2 antikoerper, ATRAB7A antikoerper, ATRABG2 antikoerper, F7D8.20 antikoerper, F7D8_20 antikoerper, RAB GTPase homolog 7A antikoerper, DDBDRAFT_0190210 antikoerper, DDBDRAFT_0191507 antikoerper, DDB_0190210 antikoerper, DDB_0191507 antikoerper, Rab7a antikoerper, rab-7 antikoerper, zgc:64058 antikoerper, RAB5A, member RAS oncogene family antikoerper, RAB7A, member RAS oncogene family antikoerper, RAB7A, member RAS oncogene family L homeolog antikoerper, rab7A protein antikoerper, RAB GTPase homolog 7A antikoerper, Rab GTPase antikoerper, ras-related protein rab-7a antikoerper, RAB7, member RAS oncogene family antikoerper, RAB5A antikoerper, RAB7A antikoerper, Rab7a antikoerper, rab7a.L antikoerper, rab7a antikoerper, rab7A antikoerper, Rab7 antikoerper, rab7 antikoerper
    Hintergrund

    Synonyms: Ras-related protein Rab-7a, RAB7A

    Background: Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism. Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function (e.g. Salmonella) and sometimes by excluding RAB7A function (e.g. Mycobacterium). In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. Controls the endosomal trafficking and neurite outgrowth signaling of NTRK1/TRKA. Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation.

    Gen-ID
    7879
    UniProt
    P51149
    Pathways
    EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom
Sie sind hier:
Kundenservice