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RNF40 Antikörper

RNF40 Reaktivität: Human, Maus, Ratte WB, IP, IHC (p) Wirt: Kaninchen Monoclonal 8D8 unconjugated
Produktnummer ABIN6944788
  • Target Alle RNF40 Antikörper anzeigen
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Reaktivität
    • 45
    • 15
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 2
    Kaninchen
    Klonalität
    • 44
    • 1
    Monoklonal
    Konjugat
    • 23
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser RNF40 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 17
    • 10
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant protein within human RNF40 aa 200-400.
    Klon
    8D8
    Isotyp
    IgG
    Top Product
    Discover our top product RNF40 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IP(1-2 μg)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
    Andere Bezeichnung
    RNF40 (RNF40 Produkte)
    Hintergrund

    Synonyms: E3 ubiquitin-protein ligase BRE1B, BRE1-B, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RING-type E3 ubiquitin transferase BRE1B, KIAA0661

    Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

    Gen-ID
    9810
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