RNF40 Antikörper
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- Target Alle RNF40 Antikörper anzeigen
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser RNF40 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within human RNF40 aa 200-400.
- Klon
- 8D8
- Isotyp
- IgG
- Top Product
- Discover our top product RNF40 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IP(1-2 μg) - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
- Andere Bezeichnung
- RNF40 (RNF40 Produkte)
- Synonyme
- AI848422 antikoerper, mKIAA0661 antikoerper, BRE1B antikoerper, RBP95 antikoerper, STARING antikoerper, ring finger protein 40 antikoerper, RNF40 antikoerper, Rnf40 antikoerper
- Hintergrund
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Synonyms: E3 ubiquitin-protein ligase BRE1B, BRE1-B, 95 kDa retinoblastoma-associated protein, RBP95, RING finger protein 40, RING-type E3 ubiquitin transferase BRE1B, KIAA0661
Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
- Gen-ID
- 9810
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