SF3B3 Antikörper

Produktnummer ABIN6944865

Produktdetails anti-SF3B3 Antikörper

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser SF3B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within the C-terminus of human SF3B3.

Klon: 5F1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SF3B3

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Andere Bezeichnung: SF3B3 (SF3B3 Produkte)

Synonyme: GB11574 antikoerper, rse1 antikoerper, sap130 antikoerper, sf3b130 antikoerper, staf130 antikoerper, sf3b3 antikoerper, 1810061H24Rik antikoerper, 5730409A01Rik antikoerper, AA409318 antikoerper, D8Ertd633e antikoerper, RSE1 antikoerper, SAP130 antikoerper, mKIAA0017 antikoerper, ik:tdsubc_2b2 antikoerper, wu:fb81f05 antikoerper, xx:tdsubc_2b2 antikoerper, zgc:55440 antikoerper, SF3b130 antikoerper, STAF130 antikoerper, splicing factor 3b subunit 3 antikoerper, splicing factor 3B subunit 3 antikoerper, splicing factor 3b, subunit 3, 130kDa antikoerper, splicing factor 3b subunit 3 L homeolog antikoerper, splicing factor 3b, subunit 3 antikoerper, SF3B3 antikoerper, LOC550935 antikoerper, sf3b3 antikoerper, Sf3b3 antikoerper, LOC100178056 antikoerper, sf3b3.L antikoerper

Hintergrund:

Synonyms: Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130 kDa subunit, STAF130, Spliceosome-associated protein 130, SF3b130, SF3B3, SAP130

Background: SF3B is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130 (also known as SF3B3), SAP 145 and SAP 155. SF3B3, SAP 145 and SAP 155 are present in a protein complex in HeLa nuclear extracts and associate with one another. While SF3B3 and SAP 155 interact with each other (directly or indirectly) within this complex, SAP 49 and SAP 145 are known to interact directly with each other. Unexpectedly, the SAP 49-SAP 145 protein-protein interaction requires the amino-terminus of SAP 49, which contains two RNA-recognition motifs. The observation that SAP 49 and SAP 145 interact directly with both U2 snRNP and the pre-mRNA suggests that this protein complex plays a role in tethering U2 snRNP to the branch site.

Gen-ID: 23450

UniProt: Q15393