SRSF3 Antikörper
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- Target Alle SRSF3 Antikörper anzeigen
- SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser SRSF3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Full length recombinant protein.
- Klon
- 9C11
- Isotyp
- IgG
- Top Product
- Discover our top product SRSF3 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
- Andere Bezeichnung
- SFRS3 (SRSF3 Produkte)
- Synonyme
- SFRS3 antikoerper, SRp20 antikoerper, AL024116 antikoerper, Sfrs3 antikoerper, X16 antikoerper, sfrs3 antikoerper, srp20 antikoerper, SRP20 antikoerper, si:zc263a23.9 antikoerper, zgc:86626 antikoerper, serine and arginine rich splicing factor 3 antikoerper, serine/arginine-rich splicing factor 3 antikoerper, serine/arginine-rich splicing factor 3 S homeolog antikoerper, serine/arginine-rich splicing factor 3a antikoerper, SRSF3 antikoerper, Srsf3 antikoerper, srsf3.S antikoerper, srsf3a antikoerper
- Hintergrund
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Synonyms: Serine/arginine-rich splicing factor 3, SRSF3, Pre-mRNA-splicing factor SRP20, Splicing factor arginine/serine-rich 3, SRP20
Background: Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export. RNA-binding is semi-sequence specific
- Gen-ID
- 6428
- UniProt
- P84103
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