SPCS2 Antikörper (AA 2-100) (HRP)

Produktnummer ABIN6945026

Produktdetails anti-SPCS2 Antikörper (HRP)

Target: SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))

Bindungsspezifität: AA 2-100

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPCS2 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB)

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPCS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SPCS2

Target: SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))

Andere Bezeichnung: SPCS2 (SPCS2 Produkte)

Synonyme: RGD1311253 antikoerper, 5730406I15Rik antikoerper, AA408713 antikoerper, mKIAA0102 antikoerper, SPC25 antikoerper, signal peptidase complex subunit 2 antikoerper, signal peptidase complex subunit 2 homolog (S. cerevisiae) antikoerper, Spcs2 antikoerper, SPCS2 antikoerper

Hintergrund:

Synonyms: Microsomal signal peptidase 25 kDa subunit, Signal peptidase complex subunit 2, Signal peptidase complex subunit 2 homolog (S. cerevisiae), SPase 25 kDa subunit, SPCS2, SPCS2_HUMAN.

Background: SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Gen-ID: 9789

UniProt: Q15005

Pathways: Peptide Hormone Metabolism