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UBA2 Antikörper

UBA2 Reaktivität: Human, Maus, Ratte WB, FACS Wirt: Kaninchen Monoclonal 4F12 unconjugated
Produktnummer ABIN6945243
  • Target Alle UBA2 Antikörper anzeigen
    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
    Reaktivität
    • 45
    • 15
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 41
    • 4
    • 1
    Kaninchen
    Klonalität
    • 36
    • 10
    Monoklonal
    Konjugat
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser UBA2 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 17
    • 15
    • 12
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Recombinant protein within human UBA2 aa 1-150
    Klon
    4F12
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB 1:300-5000
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))
    Andere Bezeichnung
    UBA2 (UBA2 Produkte)
    Hintergrund

    Synonyms: SUMO-activating enzyme subunit 2, Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, UBA2, SAE2, UBLE1B, HRIHFB2115.

    Background: UBA2 (aka SAE2) functions to induce posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, which regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins. The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

    Gen-ID
    10054
    UniProt
    Q9UBT2
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