SARS-CoV-2 Spike S1 Antikörper (RBD)

Produktnummer ABIN6952746

Produktdetails anti-SARS-CoV-2 Spike S1 Antikörper

Target: SARS-CoV-2 Spike S1

Bindungsspezifität: RBD

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARS-CoV-2 Spike S1 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Spike Protein S1 Receptor Binding Domain

Spezifität: This antibody was selected for its ability to bind to the virus SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) from the disease COVID-19.

Produktmerkmale: Rabbit anti-SARS-CoV-2 S1 RBD antibody

Aufreinigung: The IgG fraction was purified by Protein A affinity chromatography.

Immunogen: This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 S1 RBD protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA (recommended work dilution = 1:160,000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute the antibody with sterile water to a final concentration of 1 mg/mL.

Buffer: Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution.

Handhabung: Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C.

Referenzen für anti-SARS-CoV-2 Spike S1 Antikörper (ABIN6952746)

Azad, Singaravelu, Taha, Jamieson, Boulton, Crupi, Martin, Brown, Poutou, Ghahremani, Pelin, Nouri, Rezaei, Marshall, Enomoto, Arulanandam, Alluqmani, Samson, Gingras, Cameron, Greer, Ilkow, Diallo et al.: "Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." in: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).

Details zu SARS-CoV-2 Spike S1

Target: SARS-CoV-2 Spike S1

Abstract: SARS-CoV-2 Spike S1 Produkte

Synonyme: E2 antikoerper, Surface Glycoprotein antikoerper, S antikoerper

Substanzklasse: Viral Protein

Hintergrund: It's been reported that 2019-nCoV (COVID-19) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Gen-ID: 43740568

UniProt: P0DTC2