TXN Antikörper (Biotin)

Produktnummer ABIN6963928

Produktdetails anti-TXN Antikörper (Biotin)

Target: TXN (Thioredoxin (TXN))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TXN Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Spezifität: Native and recombinant Thioredoxin-1

Kreuzreaktivität (Details): The antibody cross-reacts with Trx1 from cow. For quantification of human Trx1 in ELISA, samples should not contain bovine serum.

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human Thioredoxin-1

Klon: MT13X3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: For quantification of Trx1 in solution e.g. cell culture supernatants and serum/ plasma using ELISA. MT13X3 is recommended as detection mAb in combination with coating mAb MT17R6 . MT13X3 is also suitable for Western blot.

Kommentare:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-TXN Antikörper (Biotin) (ABIN6963928)

Faghih, Rostami-Nejad, Amani, Sadeghi, Pourhoseingholi, Masotti, Zali: "Analysis of IL17A and IL21 Expression in the Small Intestine of Celiac Disease Patients and Correlation with Circulating Thioredoxin Level." in: Genetic testing and molecular biomarkers, Vol. 22, Issue 9, pp. 518-525, (2018) (PubMed).

Mahmoudian, Khalilnezhad, Gharagozli, Amani et al.: "Thioredoxin-1, redox factor-1 and thioredoxin-interacting protein, mRNAs are differentially expressed in Multiple Sclerosis patients exposed and non-exposed to interferon and immunosuppressive ..." in: Gene, Vol. 634, pp. 29-36, (2017) (PubMed).

Reiser, Mathys, Curbo, Pannecouque, Noppen, Liekens, Engman, Lundberg, Balzarini, Karlsson: "The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147773, (2016) (PubMed).

Lundberg, Curbo, Reiser, Masterman, Braesch-Andersen, Areström, Ahlborg: "Methodological aspects of ELISA analysis of thioredoxin 1 in human plasma and cerebrospinal fluid." in: PLoS ONE, Vol. 9, Issue 7, pp. e103554, (2015) (PubMed).

Details zu TXN

Target: TXN (Thioredoxin (TXN))

Andere Bezeichnung: Thioredoxin1 (TXN Produkte)

Gen-ID: 7295

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis