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NCOA3 Antikörper

NCOA3 Reaktivität: Human WB, ChIP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6971371
  • Target Alle NCOA3 Antikörper anzeigen
    NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
    Reaktivität
    • 61
    • 17
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 8
    • 1
    • 1
    Kaninchen
    Klonalität
    • 57
    • 7
    Polyklonal
    Konjugat
    • 33
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NCOA3 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 24
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Produktmerkmale
    AIB1 (Amplified in Breast Cancer 1, Steroid Receptor Coactivator-3, Nuclear Receptor Coactivator 3, SRC-3, NCOA3) is a chromatin-associated protein that interacts with nuclear hormone receptors to modify their activity as transcriptional activators. AIB1 has histone acetyltransferase (HAT) activity and recruits p300/CBP-associated factor (PCAF) and CREB binding protein (CBP) as part of a multisubunit co-activator complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. It is Involved in the coactivation of different nuclear receptors, such as GR, ER, RARs, RXRs, TRs, VDR and PPARs. It is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFkB1 protein. AIB1 / SRC-3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Human samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This AIB1 antibody was raised against a peptide derived from human AIB1/SRC-3.
    Isotyp
    IgG
    Top Product
    Discover our top product NCOA3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
    Andere Bezeichnung
    AIB1 / SRC-3 (NCOA3 Produkte)
    Synonyme
    NCOA3 antikoerper, ACTR antikoerper, AIB-1 antikoerper, AIB1 antikoerper, CAGH16 antikoerper, CTG26 antikoerper, KAT13B antikoerper, RAC3 antikoerper, SRC-3 antikoerper, SRC3 antikoerper, TNRC14 antikoerper, TNRC16 antikoerper, TRAM-1 antikoerper, bHLHe42 antikoerper, pCIP antikoerper, 2010305B15Rik antikoerper, AW321064 antikoerper, Actr antikoerper, Aib1 antikoerper, Rac3 antikoerper, Src3 antikoerper, Tram-1 antikoerper, Tram1 antikoerper, p/Cip antikoerper, pCip antikoerper, actr antikoerper, aib-1 antikoerper, aib1 antikoerper, cagh16 antikoerper, ctg26 antikoerper, kat13b antikoerper, pcip antikoerper, rac3 antikoerper, src-3 antikoerper, src3 antikoerper, tnrc14 antikoerper, tnrc16 antikoerper, tram-1 antikoerper, xSRC-3 antikoerper, nuclear receptor coactivator 3 antikoerper, nuclear receptor coactivator 3 S homeolog antikoerper, NCOA3 antikoerper, Ncoa3 antikoerper, ncoa3.S antikoerper
    Molekulargewicht
    160 kDa
    NCBI Accession
    NP_858045
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
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