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Cullin 4B Antikörper (N-Term)

CUL4B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6971562
  • Target Alle Cullin 4B (CUL4B) Antikörper anzeigen
    Cullin 4B (CUL4B)
    Bindungsspezifität
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 60
    • 22
    • 21
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 5
    Kaninchen
    Klonalität
    • 57
    • 3
    Polyklonal
    Konjugat
    • 32
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Cullin 4B Antikörper ist unkonjugiert
    Applikation
    • 40
    • 19
    • 9
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    CUL4B (Cullin 4B) is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, Histone H2A, Histone H3 and Histone H4 in response to radiation-induced DNA damage and may act as a transcriptional corepressor by ubiquitination of Histone H2AK119 and recruiting PRC2 complexes. CUL4B antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This antibody was raised against a peptide within the N-terminal region of human CUL4B.
    Isotyp
    IgG
    Top Product
    Discover our top product CUL4B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    Cullin 4B (CUL4B)
    Andere Bezeichnung
    CUL4B (CUL4B Produkte)
    Synonyme
    MRXHF2 antikoerper, MRXS15 antikoerper, MRXSC antikoerper, SFM2 antikoerper, 2700050M05Rik antikoerper, AA409770 antikoerper, CUL-4B antikoerper, mKIAA0695 antikoerper, RGD1564494 antikoerper, im:7140950 antikoerper, im:7150765 antikoerper, MGC115611 antikoerper, Tb03.1J15.620 antikoerper, sfm2 antikoerper, mrxsc antikoerper, mrxhf2 antikoerper, cullin 4B antikoerper, cullin 4B S homeolog antikoerper, CUL4B antikoerper, Cul4b antikoerper, cul4b antikoerper, cul4b.S antikoerper, Tb927.3.1290 antikoerper
    Molekulargewicht
    110 kDa
    NCBI Accession
    NP_003579
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