EZH1 Antikörper (N-Term)

Produktnummer ABIN6971640

Produktdetails anti-EZH1 Antikörper

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Bindungsspezifität: N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EZH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: EZH1 (Enhancer Of Zeste Homolog 1 ) is a Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH1-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. EZH1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

Aufreinigung: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of human EZH1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu EZH1

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Andere Bezeichnung: EZH1 (EZH1 Produkte)

Synonyme: KMT6B antikoerper, si:ch211-250i3.1 antikoerper, zgc:136829 antikoerper, AW557915 antikoerper, mKIAA0388 antikoerper, EZH1 antikoerper, enhancer of zeste 1 polycomb repressive complex 2 subunit antikoerper, EZH1 antikoerper, ezh1 antikoerper, Ezh1 antikoerper

Molekulargewicht: 100 kDa

NCBI Accession: NP_001982