FOXL2 Antikörper (N-Term)

Produktnummer ABIN6971660

Produktdetails anti-FOXL2 Antikörper

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: FOXL2 (forkhead box L2, BPES, PFRK, POF3, BPES1, PINTO) is a transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. FOXL2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Andere Bezeichnung: FOXL2 (FOXL2 Produkte)

Synonyme: BPES antikoerper, BPES1 antikoerper, PFRK antikoerper, PINTO antikoerper, POF3 antikoerper, AU045128 antikoerper, Pfrk antikoerper, FOXL2 antikoerper, zgc:136549 antikoerper, foxl2 antikoerper, FoxL2 antikoerper, foxL2 antikoerper, forkhead box L2 antikoerper, forkhead box L2a antikoerper, forkhead box L2 S homeolog antikoerper, forkhead transcription factor L2 antikoerper, foxl2 protein antikoerper, fork-head box L2 transcription factor antikoerper, FOXL2 antikoerper, Foxl2 antikoerper, foxl2a antikoerper, foxl2 antikoerper, foxl2.S antikoerper, LOC751846 antikoerper, foxL2 antikoerper

Molekulargewicht: 40 kDa

NCBI Accession: NP_075555

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity