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FOXL2 Antikörper (N-Term)

FOXL2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6971660
  • Target Alle FOXL2 Antikörper anzeigen
    FOXL2 (Forkhead Box L2 (FOXL2))
    Bindungsspezifität
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 64
    • 34
    • 21
    • 20
    • 19
    • 17
    • 6
    • 5
    • 2
    • 2
    • 1
    Human
    Wirt
    • 60
    • 4
    • 1
    Kaninchen
    Klonalität
    • 59
    • 6
    Polyklonal
    Konjugat
    • 33
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FOXL2 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 24
    • 11
    • 11
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    FOXL2 (forkhead box L2, BPES, PFRK, POF3, BPES1, PINTO) is a transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. FOXL2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2.
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    FOXL2 (Forkhead Box L2 (FOXL2))
    Andere Bezeichnung
    FOXL2 (FOXL2 Produkte)
    Molekulargewicht
    40 kDa
    NCBI Accession
    NP_075555
    Pathways
    Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
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