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H2AFV Antikörper (C-Term)

H2AFV Reaktivität: Drosophila melanogaster WB, ChIP Wirt: Maus Monoclonal 10E9-D1 unconjugated
Produktnummer ABIN6971793
  • Target Alle H2AFV Antikörper anzeigen
    H2AFV (H2A Histone Family, Member V (H2AFV))
    Bindungsspezifität
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Drosophila melanogaster
    Wirt
    • 11
    • 4
    Maus
    Klonalität
    • 11
    • 4
    Monoklonal
    Konjugat
    • 11
    • 2
    • 1
    • 1
    Dieser H2AFV Antikörper ist unkonjugiert
    Applikation
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    Produktmerkmale
    The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H2A.Z (H2AZ, H2AFZ) is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. H2A.Z is highly conserved during evolution. It plays an important role in basic cellular mechanisms such as gene activation, chromosome segregation, heterochromatic silencing and progression through the cell cycle.In Drosophila, the H2A variant corresponding to H2AZ is H2Av. H2Av is an essential protein in Drosophila and has been implicated in both activation and repression of transcription. H2Av is localized to centromeric heterochromatin in Drosophila and flies lacking H2Av have reduced levels of heterochromatin components at the centromeres. However, H2Av nucleosome distribution throughout the rest of the Drosophila genome correlates with genes that have an open and uniform chromatin architecture at promoter regions. Histone H2Av antibody (mAb) (Clone 10E9.D1) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Drosophila samples.
    Aufreinigung
    Protein A Chromatography
    Immunogen
    This antibody was raised against a peptide in the C-terminus of the Drosophila melanogaster Histone variant H2Av.
    Klon
    10E9-D1
    Isotyp
    IgG2a
    Top Product
    Discover our top product H2AFV Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    H2AFV (H2A Histone Family, Member V (H2AFV))
    Andere Bezeichnung
    Histone H2Av (H2AFV Produkte)
    Synonyme
    H2A.Z-2 antikoerper, H2afv antikoerper, H2AV antikoerper, h2av antikoerper, C530002L11Rik antikoerper, H2a.z-2 antikoerper, H2av antikoerper, H2A.F/Z antikoerper, h2afv antikoerper, h2afz antikoerper, H2A histone family, member V antikoerper, H2A histone family member V antikoerper, H2A histone family member V S homeolog antikoerper, H2A histone family, member Va antikoerper, H2afv antikoerper, LOC100226437 antikoerper, H2AFV antikoerper, h2afv.S antikoerper, h2afva antikoerper
    Molekulargewicht
    15 kDa
    NCBI Accession
    NP_524519
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