MED1 Antikörper (C-Term)

Produktnummer ABIN6972331

Produktdetails anti-MED1 Antikörper

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktmerkmale: MED1 (Mediator complex subunit 1, TRIP2, Thyroid receptor-interacting protein 2) is a component of the Mediator complex, a coactivator involved in the regulated transcription of most genes transcribed by RNA polymerase II. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. MED1 is involved in supporting hematopoietic stem and/or progenitor cell function. MED1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This MED1 antibody was raised against a peptide within the C-terminal region of human MED1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu MED1

Target: MED1 (Mediator Complex Subunit 1 (MED1))

Andere Bezeichnung: MED1 (MED1 Produkte)

Synonyme: CRSP1 antikoerper, CRSP200 antikoerper, DRIP205 antikoerper, DRIP230 antikoerper, PBP antikoerper, PPARBP antikoerper, PPARGBP antikoerper, RB18A antikoerper, TRAP220 antikoerper, TRIP2 antikoerper, CRSP-1 antikoerper, MED1 antikoerper, pbp antikoerper, nbr1 antikoerper, crsp1 antikoerper, rb18a antikoerper, trip2 antikoerper, pparbp antikoerper, crsp200 antikoerper, drip205 antikoerper, drip230 antikoerper, ppargbp antikoerper, trap220 antikoerper, CG7162 antikoerper, Dmel\\CG7162 antikoerper, Med1 antikoerper, Med1/SOP3/TRAP220 antikoerper, Trap220 antikoerper, dTRAP220 antikoerper, AI480703 antikoerper, CRSP210 antikoerper, Pparbp antikoerper, l11Jus15 antikoerper, RGD1559552 antikoerper, mediator complex subunit 1 antikoerper, calcitonin-related polypeptide beta antikoerper, Mediator complex subunit 1 antikoerper, mediator of RNA polymerase II transcription subunit 1 antikoerper, MED1 antikoerper, CALCB antikoerper, med1 antikoerper, Med1 antikoerper

Molekulargewicht: 210 kDa

NCBI Accession: NP_004765

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha