MYCN Antikörper (C-Term)

Produktnummer ABIN6972393

Produktdetails anti-MYCN Antikörper

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq)

Produktmerkmale: N-Myc (MYCN) is a member of the Myc family of proto-oncogenes. Myc family members play crucial roles in regulating cell proliferation, size and differentiation. N-Myc is required for proper development of the nervous system. Myc family proteins can induce malignant transformation inappropriately modulating gene transcription, leading to unchecked cell proliferation. Misexpression of N-Myc is often associated with pediatric neural cancers such as neuroblastoma, medulloblastoma and retinoblastoma. N-Myc antibody (pAb) was raised in a Rabbit host. It has been validated for use in ChIP-Seq and Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This N-Myc antibody was raised against a peptide derived from the C-terminal region of human N-Myc.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: N-Myc (MYCN Produkte)

Synonyme: MODED antikoerper, MYCNOT antikoerper, N-myc antikoerper, NMYC antikoerper, ODED antikoerper, bHLHe37 antikoerper, Nmyc antikoerper, Nmyc-1 antikoerper, Nmyc1 antikoerper, c-nmyc antikoerper, Nmuc1 antikoerper, fb57a02 antikoerper, nmyc1 antikoerper, wu:fb57a02 antikoerper, zgc:85706 antikoerper, XN-myc antikoerper, XNmyc antikoerper, mycn antikoerper, mycn-a antikoerper, mycn-b antikoerper, mycna antikoerper, xN-myc1 antikoerper, MYCN proto-oncogene, bHLH transcription factor antikoerper, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog antikoerper, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived antikoerper, olfactory receptor 8S1 antikoerper, MYCN proto-oncogene, bHLH transcription factor S homeolog antikoerper, MYCN antikoerper, Mycn antikoerper, LOC515887 antikoerper, mycn antikoerper, mycn.S antikoerper

Molekulargewicht: 60 kDa

NCBI Accession: NP_005369