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N6-Methyladenosine Antikörper

Reaktivität: Human, Saccharomyces cerevisiae DB, IP Wirt: Maus Monoclonal 17-3-4-1 unconjugated
Produktnummer ABIN6972397
  • Target
    N6-Methyladenosine
    Reaktivität
    Human, Saccharomyces cerevisiae
    Wirt
    • 1
    • 1
    Maus
    Klonalität
    • 1
    • 1
    Monoklonal
    Konjugat
    • 2
    Unkonjugiert
    Applikation
    Dot Blot (DB), Immunoprecipitation (IP)
    Produktmerkmale
    N6-Methyladenosine (m6A) ) is an RNA modification on the N-6 position of adenosine. This modification has been found to be abundant in the 3' UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites suggesting a potential role in epigenetic gene regulation. FTO and ALKBH are demethylases for 6-methyladenosine while a multiprotein complex that includes METTL3 functions as the methyltransferase. Recent findings revealed that m6A is also present on metazoan DNA, suggesting a genuine epigenetic role for this modification in the context of DNA as well. N6-Methyladenosine (m6A) antibody (mAb) (Clone 17-3-4-1) was raised in a Mouse host. It has been validated for use in Dot blot and Immunoprecipitation, it has been shown to react with Budding Yeast and Human samples, but the sequence is not species specific so it should react with a wide range of sample types.
    Aufreinigung
    Protein A Chromatography
    Immunogen
    This antibody was raised against 6-Methyladenosine conjugated to BSA.
    Klon
    17-3-4-1
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    N6-Methyladenosine
    Andere Bezeichnung
    N6-Methyladenosine (m6A)
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