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SATB2 Antikörper (C-Term)

SATB2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6972697
  • Target Alle SATB2 Antikörper anzeigen
    SATB2 (SATB Homeobox 2 (SATB2))
    Bindungsspezifität
    • 16
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 64
    • 34
    • 29
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 8
    Kaninchen
    Klonalität
    • 45
    • 19
    Polyklonal
    Konjugat
    • 29
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SATB2 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 23
    • 16
    • 14
    • 14
    • 8
    • 8
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    SATB2 (SATB homeobox 2, Special AT-Rich Sequence-Binding Protein 2) binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. SATB2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This antibody was raised against a peptide within the C-terminal region of human SATB2.
    Isotyp
    IgG
    Top Product
    Discover our top product SATB2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    SATB2 (SATB Homeobox 2 (SATB2))
    Andere Bezeichnung
    SATB2 (SATB2 Produkte)
    Synonyme
    RGD1562369 antikoerper, mKIAA1034 antikoerper, SATB homeobox 2 antikoerper, special AT-rich sequence binding protein 2 antikoerper, SATB2 antikoerper, satb2 antikoerper, Satb2 antikoerper
    Molekulargewicht
    90 kDa
    NCBI Accession
    NP_056080
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