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SOX2 Antikörper (C-Term)

SOX2 Reaktivität: Human, Maus WB, IF, ICC, CUT&RUN, ChIP-seq, ChIP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6972778
  • Target Alle SOX2 Antikörper anzeigen
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Bindungsspezifität
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 10
    • 10
    • 10
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 207
    • 99
    • 69
    • 21
    • 13
    • 10
    • 10
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 165
    • 47
    • 2
    Kaninchen
    Klonalität
    • 164
    • 50
    Polyklonal
    Konjugat
    • 104
    • 16
    • 15
    • 11
    • 10
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SOX2 Antikörper ist unkonjugiert
    Applikation
    • 165
    • 110
    • 51
    • 45
    • 44
    • 40
    • 40
    • 28
    • 24
    • 23
    • 17
    • 16
    • 12
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Cleavage Under Targets and Release Using Nuclease (CUT&RUN), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)
    Produktmerkmale
    Sox2 (SRY related HMG BOX gene 2) is a DNA binding transcription factor and a member of the SOX family of proteins. SOX proteins have an HMG box that binds DNA. Sox2 forms a complex with Oct-4 and controls the expression of a number of genes involved in embryonic. Sox2 is critical for early embryogenesis and for embryonic stem cell pluripotency and thus can serve as a stem cell marker. Overexpression of Sox2 (along with Oct-4, KLF4 and c-Myc) can transform mouse fibroblasts into a state resembling embryonic stem cells (ES cells), referred to as Induced Pluripotency. Defects in Sox2 are the cause of microphthalmia syndromic type 3. Sox2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This Sox2 antibody was raised against a peptide within the C-terminal region of human Sox2.
    Isotyp
    IgG
    Top Product
    Discover our top product SOX2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Janssens, Wu, Sarthy, Meers, Myers, Olson, Ahmad, Henikoff: "Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs." in: Epigenetics & chromatin, Vol. 11, Issue 1, pp. 74, (2019) (PubMed).

  • Target
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    Andere Bezeichnung
    Sox2 (SOX2 Produkte)
    Synonyme
    ANOP3 antikoerper, MCOPS3 antikoerper, RGD1565646 antikoerper, Sox-2 antikoerper, lcc antikoerper, ysb antikoerper, cb236 antikoerper, wu:fb83g04 antikoerper, wu:fc14d07 antikoerper, zgc:65860 antikoerper, zgc:77389 antikoerper, SRY-box2 antikoerper, Xsox-2 antikoerper, anop3 antikoerper, mcops3 antikoerper, sox-2 antikoerper, SRY-box 2 antikoerper, SRY box 2 antikoerper, SRY (sex determining region Y)-box 2 antikoerper, SRY-box 2 S homeolog antikoerper, SOX2 antikoerper, Sox2 antikoerper, sox2 antikoerper, sox2.S antikoerper
    Molekulargewicht
    42 kDa
    NCBI Accession
    NP_003097
    Pathways
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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