HIPK1 Antikörper (AA 1-100) (AbBy Fluor® 350)
-
- Target Alle HIPK1 Antikörper anzeigen
- HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
-
Bindungsspezifität
- AA 1-100
-
Reaktivität
- Human, Maus, Affe, Makake
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser HIPK1 Antikörper ist konjugiert mit AbBy Fluor® 350
-
Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Makake, Affe, Maus
- Homologie
- Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HIPK1
- Isotyp
- IgG
- Top Product
- Discover our top product HIPK1 Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
- Andere Bezeichnung
- HIPK1 (HIPK1 Produkte)
- Synonyme
- HIPK1 antikoerper, myak antikoerper, nbak2 antikoerper, hipk1 antikoerper, Myak antikoerper, Nbak2 antikoerper, 1110062K04Rik antikoerper, homeodomain interacting protein kinase 1 antikoerper, homeodomain interacting protein kinase 1 L homeolog antikoerper, homeodomain interacting protein kinase 1 S homeolog antikoerper, HIPK1 antikoerper, hipk1.L antikoerper, hipk1 antikoerper, hipk1.S antikoerper, Hipk1 antikoerper
- Hintergrund
-
Synonyms: Hipk 1, Hipk1, HIPK1_HUMAN, Homeodomain interacting protein kinase 1, Homeodomain interacting protein kinase 1 like protein, Homeodomain-interacting protein kinase 1, Myak, Nbak 2, Nbak2, Nuclear body associated kinase 2, Nuclear body associated kinase 2b
Background: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.
- Gen-ID
- 204851
- UniProt
- Q86Z02
-