HTRA2 Antikörper (AA 231-330) (AbBy Fluor® 488)

Produktnummer ABIN6977839

Produktdetails anti-HTRA2 Antikörper (AbBy Fluor® 488)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Bindungsspezifität: AA 231-330

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HTRA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HTRA2 (HTRA2 Produkte)

Synonyme: CG8464 antikoerper, DmHtrA2 antikoerper, Dmel\\CG8464 antikoerper, HtrA2/Omi antikoerper, Omi antikoerper, dOmi antikoerper, domi antikoerper, htrA2 antikoerper, omi antikoerper, HTRA2 antikoerper, PRSS25 antikoerper, OMI antikoerper, PARK13 antikoerper, AI481710 antikoerper, Prss25 antikoerper, mnd2 antikoerper, HTRA2-related serine protease antikoerper, HtrA serine peptidase 2 antikoerper, HtrA2 antikoerper, HTRA2 antikoerper, htra2 antikoerper, Htra2 antikoerper

Hintergrund:

Synonyms: Serine protease HTRA2, mitochondrial, HTRA2, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25 Serine proteinase OMI, HTRA2, OMI, PRSS25

Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

Gen-ID: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity