CILP Antikörper (AA 1051-1184) (AbBy Fluor® 555)
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- Target Alle CILP Antikörper anzeigen
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
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Bindungsspezifität
- AA 1051-1184
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CILP Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Spezifität
- The immunogen falls within the Cartilage intermediate layer protein 1 C2 region.
- Kreuzreaktivität
- Human, Ratte
- Homologie
- Mouse,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CILP
- Isotyp
- IgG
- Top Product
- Discover our top product CILP Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))
- Andere Bezeichnung
- CILP (CILP Produkte)
- Synonyme
- CILP-1 antikoerper, HsT18872 antikoerper, 9830114D16 antikoerper, C130036G17Rik antikoerper, NTPPH antikoerper, CILP antikoerper, im:7137994 antikoerper, cartilage intermediate layer protein antikoerper, cartilage intermediate layer protein, nucleotide pyrophosphohydrolase antikoerper, cartilage intermediate layer protein 1 antikoerper, CILP antikoerper, Cilp antikoerper, cilp antikoerper, LOC100336614 antikoerper
- Hintergrund
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Synonyms: CILP-1, HsT18872, Cartilage intermediate layer protein 1, Cartilage intermediate-layer protein, CILP, UNQ602/PRO1188
Background: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage.
- Gen-ID
- 8483
- UniProt
- O75339
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