CBX4 Antikörper (AA 401-500) (AbBy Fluor® 555)
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- Target Alle CBX4 Antikörper anzeigen
- CBX4 (Chromobox Homolog 4 (CBX4))
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Bindungsspezifität
- AA 401-500
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CBX4 Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CBX4
- Isotyp
- IgG
- Top Product
- Discover our top product CBX4 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CBX4 (Chromobox Homolog 4 (CBX4))
- Andere Bezeichnung
- CBX4 (CBX4 Produkte)
- Synonyme
- MPc2 antikoerper, PC2 antikoerper, NBP16 antikoerper, XPolycomb antikoerper, cbx4-a antikoerper, im:6911625 antikoerper, zgc:158588 antikoerper, chromobox 4 antikoerper, chromobox 4 S homeolog antikoerper, chromobox homolog 4 antikoerper, chromobox homolog 4 (Pc class homolog, Drosophila) antikoerper, CBX4 antikoerper, Cbx4 antikoerper, cbx4.S antikoerper, cbx4 antikoerper
- Hintergrund
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Synonyms: PC2, NBP16, E3 SUMO-protein ligase CBX4, Chromobox protein homolog 4, Polycomb 2 homolog, hPc2, CBX4
Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
- Gen-ID
- 8535
- UniProt
- O00257
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