VPS4B Antikörper (AA 301-400) (AbBy Fluor® 647)
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- Target Alle VPS4B (vps4b) Antikörper anzeigen
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Human, Maus, Fisch
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser VPS4B Antikörper ist konjugiert mit AbBy Fluor® 647
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Fisch, Human, Maus
- Homologie
- Rat,Cow,Pig
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human VPS4B
- Isotyp
- IgG
- Top Product
- Discover our top product vps4b Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))
- Andere Bezeichnung
- VPS4B (vps4b Produkte)
- Synonyme
- zgc:63682 antikoerper, vps4a antikoerper, SKD1 antikoerper, SKD1B antikoerper, VPS4-2 antikoerper, 8030489C12Rik antikoerper, Skd1 antikoerper, vacuolar protein sorting 4 homolog B antikoerper, vacuolar protein sorting 4 homolog B S homeolog antikoerper, vacuolar protein sorting 4b homolog B (S. cerevisiae) antikoerper, vacuolar protein sorting 4 homolog B (S. cerevisiae) antikoerper, vacuolar protein sorting 4B antikoerper, Vps4b antikoerper, vps4b.S antikoerper, vps4b antikoerper, VPS4B antikoerper
- Hintergrund
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Synonyms: 8030489C12Rik, Cell migration inducing 1, Cell migration-inducing gene 1 protein, MGC116271, MIG1, Protein SKD1, Skd1, SKD1B, Suppressor of K(+) transport growth defect 1, Suppressor of K+ transport defect 1, Vacuolar protein sorting 4 homolog B (S. cerevisiae), Vacuolar protein sorting 4 homolog B, Vacuolar protein sorting 4b, Vacuolar protein sorting-associated protein 4B, Vacuolar protein sorting-associating protein 4B, VPS4 2, VPS42, Vps4b, VPS4B_HUMAN.
Background: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).
- Gen-ID
- 9525
- UniProt
- O75351
- Pathways
- Microtubule Dynamics, CXCR4-mediated Signaling Events
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