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ERO1LB Antikörper (AA 1-100) (AbBy Fluor® 647)

ERO1LB Reaktivität: Maus, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN6979939
  • Target Alle ERO1LB Antikörper anzeigen
    ERO1LB (ERO1-Like beta (ERO1LB))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 25
    • 23
    • 16
    Maus, Ratte
    Wirt
    • 37
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERO1LB Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 33
    • 20
    • 17
    • 13
    • 12
    • 12
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Pig,Rabbit,Guinea Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ERO1LB
    Isotyp
    IgG
    Top Product
    Discover our top product ERO1LB Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ERO1LB (ERO1-Like beta (ERO1LB))
    Andere Bezeichnung
    ERO1LB (ERO1LB Produkte)
    Synonyme
    RGD1563548 antikoerper, 1300013B24Rik antikoerper, 1700065B09Rik antikoerper, AI447560 antikoerper, ero1-beta antikoerper, endoplasmic reticulum oxidoreductase 1 beta antikoerper, ERO1-like beta (S. cerevisiae) antikoerper, Ero1b antikoerper, ERO1B antikoerper, Ero1lb antikoerper
    Hintergrund

    Synonyms: Endoplasmic oxidoreductin-1-like protein B, ERO1-L-beta, ERO1B, ERO1-like protein beta, Oxidoreductin-1-L-beta

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

    Gen-ID
    56605
    UniProt
    Q86YB8
    Pathways
    SARS-CoV-2 Protein Interaktom
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