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Importin 8 Antikörper (AA 1-100) (AbBy Fluor® 647)

IPO8 Reaktivität: Ratte IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 647
Produktnummer ABIN6980266
  • Target Alle Importin 8 (IPO8) Antikörper anzeigen
    Importin 8 (IPO8)
    Bindungsspezifität
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    • 1
    Ratte
    Wirt
    • 32
    • 1
    • 1
    Kaninchen
    Klonalität
    • 33
    • 1
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Importin 8 Antikörper ist konjugiert mit AbBy Fluor® 647
    Applikation
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Cow,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Importin 8
    Isotyp
    IgG
    Top Product
    Discover our top product IPO8 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Importin 8 (IPO8)
    Andere Bezeichnung
    Importin 8 (IPO8 Produkte)
    Synonyme
    IPO8 antikoerper, si:ch211-116i17.1 antikoerper, RANBP8 antikoerper, 6230418K12Rik antikoerper, Abcc10 antikoerper, C130009K11Rik antikoerper, MRP7 antikoerper, OM-1 antikoerper, Om1 antikoerper, Ranbp8 antikoerper, importin 8 antikoerper, IPO8 antikoerper, ipo8 antikoerper, Ipo8 antikoerper
    Hintergrund

    Synonyms: FLJ26580, Imp 8, Imp8, Importin-8, Importin8, IPO 8, IPO8, IPO8_HUMAN, Ran binding protein 8, RAN BP8, Ran-binding protein 8, RANBP 8, RANBP8.

    Background: Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.

    Gen-ID
    10526
    UniProt
    O15397
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