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CMKLR1 Antikörper (AA 171-280) (AbBy Fluor® 680)

CMKLR1 Reaktivität: Human, Maus WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 680
Produktnummer ABIN6980622
  • Target Alle CMKLR1 Antikörper anzeigen
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Bindungsspezifität
    • 16
    • 14
    • 14
    • 12
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-280
    Reaktivität
    • 74
    • 40
    • 24
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 75
    • 3
    • 2
    Kaninchen
    Klonalität
    • 74
    • 5
    • 1
    Polyklonal
    Konjugat
    • 31
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CMKLR1 Antikörper ist konjugiert mit AbBy Fluor® 680
    Applikation
    • 60
    • 27
    • 25
    • 25
    • 19
    • 13
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Dog,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CMKLR1
    Isotyp
    IgG
    Top Product
    Discover our top product CMKLR1 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    Andere Bezeichnung
    CMKLR1 (CMKLR1 Produkte)
    Synonyme
    CHEMERINR antikoerper, ChemR23 antikoerper, DEZ antikoerper, RVER1 antikoerper, Gpcr27 antikoerper, mcmklr1 antikoerper, si:ch211-240b21.3 antikoerper, CMLKR1 antikoerper, Cmklr-1 antikoerper, GPCR antikoerper, chemerin chemokine-like receptor 1 antikoerper, chemokine-like receptor 1 antikoerper, CMKLR1 antikoerper, Cmklr1 antikoerper, cmklr1 antikoerper
    Hintergrund

    Synonyms: Chemokine receptor-like 1, CHEMR23, ChemR23, DEZ, Chemokine like receptor 1, G protein coupled receptor ChemR23, G protein coupled receptor DEZ, CML1_HUMAN , Orphan G protein coupled receptor.

    Background: Chemokine-Like Receptor 1 (CMKLR1) is a serpentine transmembrane G-protein linked receptor. It is an orphan chemoattractant receptor, also known as ChemR23 or DEZ. CMKLR1 is expressed on the surface of monocyte-derived immature dendritic cells and peripheral plamacytoid dendritic (pDC) cells, but not on myeloid dendritic (mDC) cells, monocytes and lymphocytes. The expression of CMKLR1 on pDC is down-regulated after activation. Chemerin (TIG2) is a natural ligand of CMKLR1. The interaction of CMKLR1 with Chemerin induces pDC activation and chemotaxis. It has been shown that CMKLR1 is a coreceptor for several strains of SIV and HIV-1. CMKLR1 is a potential useful marker for distinguishing pDCs and mDCs.

    Gen-ID
    1240
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