PKC iota Antikörper (AA 181-280) (AbBy Fluor® 680)
-
- Target Alle PKC iota (PRKCI) Antikörper anzeigen
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
-
Bindungsspezifität
- AA 181-280
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PKC iota Antikörper ist konjugiert mit AbBy Fluor® 680
-
Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Cow,Sheep,Pig,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PKC iota/PKCI
- Isotyp
- IgG
- Top Product
- Discover our top product PRKCI Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- Andere Bezeichnung
- PKC iota (PRKCI Produkte)
- Synonyme
- DXS1179E antikoerper, PKCI antikoerper, nPKC-iota antikoerper, aPKC[l] antikoerper, hal antikoerper, has antikoerper, PRKCI antikoerper, PKC antikoerper, 2310021H13Rik antikoerper, AI427505 antikoerper, PKClambda antikoerper, Pkci antikoerper, Pkcl antikoerper, Prkcl antikoerper, aPKClambda antikoerper, mKIAA4165 antikoerper, protein kinase C iota antikoerper, protein kinase C, iota antikoerper, PRKCI antikoerper, prkci antikoerper, Prkci antikoerper
- Hintergrund
-
Synonyms: aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type.
Background: This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]
- Gen-ID
- 5584
- UniProt
- P41743
- Pathways
- Neurotrophin Signalübertragung, Cell-Cell Junction Organization, Tube Formation
-