STK24 Antikörper (pThr178) (Biotin)
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- Target Alle STK24 Antikörper anzeigen
- STK24 (serine/threonine Kinase 24 (STK24))
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Bindungsspezifität
- pThr178
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STK24 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthesised phosphopeptide derived from human MST3 around the phosphorylation site of Thr178
- Isotyp
- IgG
- Top Product
- Discover our top product STK24 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- STK24 (serine/threonine Kinase 24 (STK24))
- Andere Bezeichnung
- MST3 (STK24 Produkte)
- Synonyme
- MST3 antikoerper, MST3B antikoerper, STE20 antikoerper, STK3 antikoerper, 1810013H02Rik antikoerper, C76483 antikoerper, MST-3 antikoerper, Mst3 antikoerper, Mst3b antikoerper, RGD1561742 antikoerper, stk24 antikoerper, wu:fi29b08 antikoerper, zgc:66137 antikoerper, 0610042I06Rik antikoerper, MST antikoerper, Mst2 antikoerper, Ste20 antikoerper, mess1 antikoerper, zgc:163071 antikoerper, mst3 antikoerper, mst3b antikoerper, ste20 antikoerper, stk3 antikoerper, serine/threonine kinase 24 antikoerper, serine/threonine kinase 24b (STE20 homolog, yeast) antikoerper, serine/threonine-protein kinase 24 antikoerper, serine/threonine kinase 3 antikoerper, serine/threonine kinase 24a (STE20 homolog, yeast) antikoerper, serine/threonine kinase 24 L homeolog antikoerper, STK24 antikoerper, Stk24 antikoerper, stk24b antikoerper, ATEG_04314 antikoerper, ATEG_09179 antikoerper, UREG_03984 antikoerper, BDBG_07988 antikoerper, MCYG_07323 antikoerper, Stk3 antikoerper, stk24a antikoerper, stk24.L antikoerper
- Hintergrund
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Synonyms: MST3 (phospho T178), p-MST3 (phospho T178), Kinase responsive to stress 1, KRS1, Mammalian STE20 like protein kinase 2, Mammalian sterile 20-like 2, Mess1, MST, MST-2, MST2, Mst3, Serine/threonine kinase 3 (STE20 homolog, yeast), Serine/threonine kinase 3 (Ste20, yeast homolog), Serine/threonine protein kinase 3, Serine/threonine protein kinase Krs1, STE20 like kinase MST2.
Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
- Gen-ID
- 8428
- UniProt
- Q9Y6E0
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