Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HMGN2 Antikörper (Biotin)

HMGN2 Reaktivität: Ratte, Maus IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN6982662
  • Target Alle HMGN2 Antikörper anzeigen
    HMGN2 (High Mobility Group Nucleosomal Binding Domain 2 (HMGN2))
    Reaktivität
    • 43
    • 22
    • 22
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Ratte, Maus
    Wirt
    • 44
    • 1
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 27
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HMGN2 Antikörper ist konjugiert mit Biotin
    Applikation
    • 25
    • 23
    • 13
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HMGN2/HMG17:2-60/90
    Isotyp
    IgG
    Top Product
    Discover our top product HMGN2 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    HMGN2 (High Mobility Group Nucleosomal Binding Domain 2 (HMGN2))
    Andere Bezeichnung
    HMGN2/HMG17 (HMGN2 Produkte)
    Synonyme
    HMG17 antikoerper, HMG-17 antikoerper, Hmg17 antikoerper, HMGN4 antikoerper, high mobility group nucleosomal binding domain 2 antikoerper, high mobility group nucleosomal binding domain 4 antikoerper, HMGN2 antikoerper, Hmgn2 antikoerper, HMGN4 antikoerper
    Hintergrund

    Synonyms: High mobility group (nonhistone chromosomal) protein 17, high mobility group nucleosomal binding domain 2, High mobility group nucleosome-binding domain-containing protein 2, High mobility group protein N2, HMG17, HMGN2, HMGN2_HUMAN, MGC5629, Non histone chromosomal protein HMG 17, Non-histone chromosomal protein HMG-17, Nonhistone chromosomal protein HMG 17, nonhistone chromosomal protein hmg-17.

    Background: The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription (15). HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates (13,5). HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence (13). Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber (13). In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development (2). Post-translational modifications : Phosphorylation favors cytoplasmic localization. Similarity : Belongs to the HMGN family.

    Gen-ID
    3151
    UniProt
    P05204
Sie sind hier:
Kundenservice