LNX1 Antikörper (AA 101-200) (Biotin)

Produktnummer ABIN6982670

Produktdetails anti-LNX1 Antikörper (Biotin)

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Bindungsspezifität: AA 101-200

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LNX1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LNX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Andere Bezeichnung: LNX1 (LNX1 Produkte)

Synonyme: LNX1 antikoerper, fj78f06 antikoerper, lnx antikoerper, si:dkey-12h2.1 antikoerper, wu:fj78f06 antikoerper, zgc:152906 antikoerper, Lnx antikoerper, LNX antikoerper, MPDZ antikoerper, PDZRN2 antikoerper, ligand of numb-protein X 1 antikoerper, LNX1 antikoerper, lnx1 antikoerper, Lnx1 antikoerper

Hintergrund:

Synonyms: E3 ubiquitin protein ligase LNX, Ligand of Numb protein X 1, Ligand of numb protein X 1 E3 ubiquitin protein ligase, LNX, LNX1, LNX1_HUMAN, MPDZ, Multi PDZ domain containing protein E3 ubiquitin protein ligase LNX, Numb binding protein 1, PDZ domain-containing ring finger protein 2, PDZRN2.

Background: Lnx1 is a membrane-bound protein that is involved in signal transduction and protein interactions. Lnx1 is an E3 Ubiquitin ligase protein that mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Lnx1 mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.

Gen-ID: 84708

UniProt: Q8TBB1