TUBA1B Antikörper (AA 401-451) (Biotin)

Produktnummer ABIN6982747

Produktdetails anti-TUBA1B Antikörper (Biotin)

Target: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Bindungsspezifität: AA 401-451

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBA1B Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TUBA1A + TUBA1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu TUBA1B

Target: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Andere Bezeichnung: TUBA1A + TUBA1B (TUBA1B Produkte)

Synonyme: RGD1565476 antikoerper, K-ALPHA-1 antikoerper, cb944 antikoerper, fb22g06 antikoerper, tuba1 antikoerper, wu:fb22g06 antikoerper, Tuba2 antikoerper, TUBA3 antikoerper, k-alpha-1 antikoerper, tuba antikoerper, Calpha1 antikoerper, Tuba1 antikoerper, TUBA1B antikoerper, tubulin, alpha 1B antikoerper, tubulin alpha 1b antikoerper, tubulin, alpha 1b antikoerper, tubulin alpha 1b L homeolog antikoerper, tubulin alpha-1B chain antikoerper, Tubulin alpha-1B chain antikoerper, Tuba1b antikoerper, TUBA1B antikoerper, tuba1b antikoerper, tuba1b.L antikoerper, LOC100445003 antikoerper, LOC102178700 antikoerper

Hintergrund:

Synonyms: TUBA1A + TUBA1B, Tubulin, Alpha 1b, Tubulin Alpha-Ubiquitous Chain, Alpha-Tubulin Ubiquitous, Tubulin K-Alpha-1, Tubulin, Alpha, Ubiquitous, Tubulin Alpha-1B Chain, Alpha Tubulin, Ubiquitous, K-ALPHA-1, Tubulin Alpha, TBA1B_HUMAN, Tubulin, Alpha 1a, TUBA3, Tubulin Alpha-3 Chain, Tubulin B-Alpha-1, LIS3, Tubulin, Alpha, Brain-Specific, Tubulin Alpha-1A Chain, Alpha-Tubulin 3, Brain-Specific, Hum-A-Tub1, Hum-A-Tub2, B-ALPHA-1, TBA1A_HUMAN, ,____alpha

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

Gen-ID: 7846

UniProt: Q71U36

Pathways: Microtubule Dynamics, M Phase