Znf423 Antikörper (AA 191-290) (Biotin)

Produktnummer ABIN6982940

Der Kaninchen Polyklonal Anti-Znf423-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Znf423 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Znf423 Antikörper (AA 191-290) (Biotin) (ABIN6982940)

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Znf423 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Znf423 Antikörper (Biotin)

Bindungsspezifität: AA 191-290

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF423

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Znf423

Target: Znf423 (Zinc Finger Protein 423 (Znf423))

Andere Bezeichnung: ZNF423

Hintergrund:

Synonyms: Early B cell factor associated zinc finger protein, Ebfaz, hOAZ, Nur12, OAZ, OLF 1/EBF associated zinc finger, OLF1/EBF associated zinc finger protein, Olf1/EBF-associated zinc finger protein, Roaz, Smad and Olf interacting zinc finger protein, Smad- and Olf-interacting zinc finger protein, Zfp104, ZFP423, zinc finger protein 423, mouse, homolog of, Zinc finger protein 423, ZN423_HUMAN, ZNF423, ZNF423 zinc finger protein 423.

Background: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Gen-ID: 23090

UniProt: Q2M1K9