SMAD9 Antikörper (AA 351-450) (Biotin)

Produktnummer ABIN6983069

Produktdetails anti-SMAD9 Antikörper (Biotin)

Target: SMAD9 (SMAD Family Member 9 (SMAD9))

Bindungsspezifität: AA 351-450

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD9 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMAD8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SMAD9

Target: SMAD9 (SMAD Family Member 9 (SMAD9))

Andere Bezeichnung: SMAD8 (SMAD9 Produkte)

Synonyme: SMAD8 antikoerper, MADH6 antikoerper, MADH9 antikoerper, PPH2 antikoerper, SMAD8A antikoerper, SMAD8B antikoerper, Madh8 antikoerper, Madh9 antikoerper, Smad8 antikoerper, SMAD family member 9 antikoerper, SMAD9 antikoerper, smad9 antikoerper, Smad9 antikoerper

Hintergrund:

Synonyms: AI528653 , BSP 1 , BSP1 , DKFZp781C1895 , DKFZp781O1323 , Dwarfin A , Dwf A , DwfA , Dwfc , hSMAD1 , hSmad5 , JV 41 , JV4 1 , JV41 , JV5 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 9 , MAD homolog 1 , MAD homolog 9 , MAD homolog1 (mothers against decapentaplegic, Drosophila) ,

Background: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway

Gen-ID: 142891

UniProt: Q96LT4