KREMEN2 Antikörper (AA 351-450) (Cy3)

Produktnummer ABIN6983428

Produktdetails anti-KREMEN2 Antikörper (Cy3)

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Bindungsspezifität: AA 351-450

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KREMEN2 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KREMEN2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KREMEN2

Target: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Andere Bezeichnung: KREMEN2 (KREMEN2 Produkte)

Synonyme: krm2 antikoerper, KREMEN2 antikoerper, MGC147633 antikoerper, KRM2 antikoerper, 2900054E04Rik antikoerper, Krm2 antikoerper, kringle containing transmembrane protein 2 S homeolog antikoerper, kringle containing transmembrane protein 2 antikoerper, kremen2.S antikoerper, KREMEN2 antikoerper, kremen2 antikoerper, Kremen2 antikoerper

Hintergrund:

Synonyms: Dickkopf receptor 2, KREM2_HUMAN, KREMEN 2, Kremen protein 2, Kremen protein 2 precursor, Kremen2, Kringle containing protein marking the eye and the nose, Kringle containing transmembrane protein 2, Kringle domain containing transmembrane protein 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KRM 2, KRM2, MGC10791, MGC16709.

Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Gen-ID: 79412

UniProt: Q8NCW0

Pathways: WNT Signalweg