CELF3 Antikörper (AA 401-465) (Cy5)

Produktnummer ABIN6984149

Produktdetails anti-CELF3 Antikörper (Cy5)

Target: CELF3 (CUGBP, Elav-Like Family Member 3 (CELF3))

Bindungsspezifität: AA 401-465

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELF3 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CELF3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CELF3

Target: CELF3 (CUGBP, Elav-Like Family Member 3 (CELF3))

Andere Bezeichnung: CELF3 (CELF3 Produkte)

Hintergrund:

Synonyms: Bruno-like protein 1, BRUNOL1, CAG repeat protein 4, CAGH4, CELF-3, CELF3, CELF3_HUMAN, CUG-BP- and ETR-3-like factor 3, CUGBP Elav-like family member 3, ELAV-type RNA-binding protein 1, ERDA4, ETR-1, Expanded repeat domain protein CAG/CTG 4, RNA-binding protein BRUNOL-1, TNRC4, Trinucleotide repeat-containing gene 4 protein.

Background: RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Gen-ID: 11189

UniProt: Q5SZQ8