SYNE1 Antikörper (AA 51-150) (Cy5)

Produktnummer ABIN6984458

Produktdetails anti-SYNE1 Antikörper (Cy5)

Target: SYNE1 (Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1))

Bindungsspezifität: AA 51-150

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNE1 Antikörper ist konjugiert mit Cy5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nesprin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SYNE1

Target: SYNE1 (Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1))

Andere Bezeichnung: Nesprin 1 (SYNE1 Produkte)

Synonyme: 8B antikoerper, ARCA1 antikoerper, C6orf98 antikoerper, CPG2 antikoerper, EDMD4 antikoerper, MYNE1 antikoerper, Nesp1 antikoerper, SCAR8 antikoerper, dJ45H2.2 antikoerper, A330049M09Rik antikoerper, BE692247 antikoerper, C130039F11Rik antikoerper, Myne1 antikoerper, mKIAA1756 antikoerper, SYNE1 antikoerper, MGC160118 antikoerper, Myne-1 antikoerper, spectrin repeat containing nuclear envelope protein 1 antikoerper, spectrin repeat containing, nuclear envelope 1 antikoerper, SYNE1 antikoerper, Syne1 antikoerper, syne1 antikoerper

Hintergrund:

Synonyms: CPG2, Enaptin, Myne-1, MYNE1, Myocyte nuclear envelope protein 1, Nesprin-1, Nuclear envelope spectrin repeat protein 1, SCAR8, Synaptic nuclear envelope protein 1, Syne-1, SYNE1, SYNE1_HUMAN, SYNE1B.

Background: Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Required for centrosome migration to the apical cell surface during early ciliogenesis.

Gen-ID: 23345

UniProt: Q8NF91

Pathways: Maintenance of Protein Location