TTC3 Antikörper (AA 251-350) (HRP)
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- Target Alle TTC3 Antikörper anzeigen
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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Bindungsspezifität
- AA 251-350
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TTC3 Antikörper ist konjugiert mit HRP
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RNF105
- Isotyp
- IgG
- Top Product
- Discover our top product TTC3 Primärantikörper
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- Applikationshinweise
- IHC-P 1:200-400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- Andere Bezeichnung
- RNF105 (TTC3 Produkte)
- Synonyme
- DCRR1 antikoerper, RNF105 antikoerper, TPRDIII antikoerper, 2610202A04Rik antikoerper, AA409221 antikoerper, D16Ium21 antikoerper, D16Ium21e antikoerper, TPRD antikoerper, mKIAA4119 antikoerper, TTC3 antikoerper, tetratricopeptide repeat domain 3 antikoerper, E3 ubiquitin-protein ligase TTC3 antikoerper, TTC3 antikoerper, Ttc3 antikoerper, LOC100562480 antikoerper
- Hintergrund
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Synonyms: DCRR1, E3 ubiquitin protein ligase TTC3, E3 ubiquitin-protein ligase TTC3, Protein DCRR1, RING finger protein 105,Tetratricopeptide repeat protein 3 (TPR repeat protein D), Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, TPRD, TPRDI, TPRDII, TPRDIII, TTC3, TTC3_HUMAN.
Background: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
- Gen-ID
- 7267
- UniProt
- P53804
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