KDM4C Antikörper (AA 291-390)

Produktnummer ABIN6989007

Produktdetails anti-KDM4C Antikörper

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Bindungsspezifität: AA 291-390

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM4C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GASC1/KDM4C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Andere Bezeichnung: GASC1/KDM4C (KDM4C Produkte)

Hintergrund:

Synonyms: GASC 1 protein, GASC1 antibody Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain containing histone demethylation protein 3C, Jumonji domain containing protein 2C, KDM4C_HUMAN.

Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Gen-ID: 23081

UniProt: Q9H3R0

Pathways: Nuclear Hormone Receptor Binding, Warburg Effekt