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JNK1/2 Antikörper (AA 131-230)

Reaktivität: Human, Maus, Ratte WB, IF (p), IF (cc), ELISA, IHC (fro), IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6989142
  • Target Alle JNK1/2 Produkte
    JNK1/2
    Bindungsspezifität
    • 14
    • 4
    • 4
    • 1
    AA 131-230
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 19
    • 1
    Kaninchen
    Klonalität
    • 19
    • 1
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JNK1/2 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Cow,Sheep,Pig,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human JNK1+JNK2
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    JNK1/2
    Andere Bezeichnung
    JNK1+JNK2 (JNK1/2 Produkte)
    Hintergrund

    Synonyms: JNK1 + JNK2, JNK1 + 2, JNK1/2, c Jun N terminal kinase 1, JNK1, JNK2, JAK 1A, JAK1A, JNK 1, JNK 46, JNK, JNK1A2, JNK21B1/2, MAPK 8, MAPK8, Mitogen activated protein kinase 8, PRKM 8, PRKM8, Protein kinase JNK1, SAPK 1, SAPK gamma, SAPK1, c-Jun, Stress activated protein kinase JNK1, Tyrosine protein kinase JAK1, MK08_HUMAN.

    Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jun 2013]

    Gen-ID
    5599
    UniProt
    P45983
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