STK24 Antikörper (pThr178)

Produktnummer ABIN6989149

Produktdetails anti-STK24 Antikörper

Target: STK24 (serine/threonine Kinase 24 (STK24))

Bindungsspezifität: pThr178

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human MST3 around the phosphorylation site of Thr178

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu STK24

Target: STK24 (serine/threonine Kinase 24 (STK24))

Andere Bezeichnung: MST3 (STK24 Produkte)

Synonyme: MST3 antikoerper, MST3B antikoerper, STE20 antikoerper, STK3 antikoerper, 1810013H02Rik antikoerper, C76483 antikoerper, MST-3 antikoerper, Mst3 antikoerper, Mst3b antikoerper, RGD1561742 antikoerper, stk24 antikoerper, wu:fi29b08 antikoerper, zgc:66137 antikoerper, 0610042I06Rik antikoerper, MST antikoerper, Mst2 antikoerper, Ste20 antikoerper, mess1 antikoerper, zgc:163071 antikoerper, mst3 antikoerper, mst3b antikoerper, ste20 antikoerper, stk3 antikoerper, serine/threonine kinase 24 antikoerper, serine/threonine kinase 24b (STE20 homolog, yeast) antikoerper, serine/threonine-protein kinase 24 antikoerper, serine/threonine kinase 3 antikoerper, serine/threonine kinase 24a (STE20 homolog, yeast) antikoerper, serine/threonine kinase 24 L homeolog antikoerper, STK24 antikoerper, Stk24 antikoerper, stk24b antikoerper, ATEG_04314 antikoerper, ATEG_09179 antikoerper, UREG_03984 antikoerper, BDBG_07988 antikoerper, MCYG_07323 antikoerper, Stk3 antikoerper, stk24a antikoerper, stk24.L antikoerper

Hintergrund:

Synonyms: MST3 (phospho T178), p-MST3 (phospho T178), Kinase responsive to stress 1, KRS1, Mammalian STE20 like protein kinase 2, Mammalian sterile 20-like 2, Mess1, MST, MST-2, MST2, Mst3, Serine/threonine kinase 3 (STE20 homolog, yeast), Serine/threonine kinase 3 (Ste20, yeast homolog), Serine/threonine protein kinase 3, Serine/threonine protein kinase Krs1, STE20 like kinase MST2.

Background: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

Gen-ID: 8428

UniProt: Q9Y6E0